Ключевые слова: рак грудной железы, хирургическое лечение, лучевой патоморфоз, реконструктивная тактика, качество жизн
SUMMARY
Shutov S.V. “An option of the optimization of a skin bound resection in surgical interventions for mammary gland cancer patients”. – Manuscript.
The thesis for a candidate medical science degree according to a speciality 14.01.10. - Oncology. -State institution "Naitional Cancer Institute", Kiev, 2008.
There are a new theoretical and practical solving of the scientific problem to improve the reconstructive tactics of a composite treatment for a mammary gland cancer patients. It includes the devising of a modificated method of a reconstructive surgery, taking into account the skin radial pathomorphosis after carring out the radiotherapy before the surgical operation. For the first time the natural ultrastructural radial pathomorphosis of a mammary gland skin was investigated. The quantitative estimation of it's morphological tissue and cellular reconstruction within different coordinative areas was done. Clinical and morphological analysis permited to base the determination method of a bound skin excision after a local radiotherapy before the surgical operation.The method of patient’s quality of life estimating was suggested to determine the effectiveness of a reconstructive tactics. Obtained rezults confirm an influence of the mammary gland reconstruction for all quality of life components.
Key words: mammary gland cancer, surgical treatment, X-ray pathomorphosis, reconstructive tactics, quality of life .
ПЕРЕЛІК УМОВНИХ СКОРОЧЕНЬ
ГЗ – грудна залоза
ЗТП – зональна топографія пухлини
ІШК – індекс шкірного клаптя
КЗ – координатна зона
ЛПТ – локальна променева терапія
ППТ – предопераційна променева терапія
ППШ – променевий патоморфоз шкіри
ПРАЛ – переміщений ректоабдомінальний лоскут
ПТ – променева терапія
РГЗ – рак грудної залози
РМЕ – радикальна мастектомія
РОД – разова очагова доза
СОД – сумарна очагова доза
ШК – шкірний клапоть
ЯЖ – якість життя
8-09-2015, 22:33